GEO Data Sets

GEO Data Sets widget icon

Provides access to data sets from gene expression omnibus (GEO DataSets).

Signals

Inputs:

  • (None)

Outputs:

  • Data

Data set selected in the widget with genes or samples in rows.

Description

GEO DataSets is a data base of gene expression curated profiles maintained by NCBI and included in the Gene Expression Omnibus. This Orange widget provides access to all its data sets and outputs a data set selected for further processing. For convenience, each dowloaded data set is stored locally.

GEO Data Sets widget

  1. Information on the GEO data set collection. Cached data sets are the ones currently stored on the computer.
  2. Output features. If Genes or spots is selected, genes (or spots) will be used as attributes. Alternatively samples will be used as attributes. Merge spots of same gene averages measures of the same gene. Finally, in the Data set name you can rename the output data. GEO title will be used as a default name.
  3. If Auto commit is on, then the selected data set will be automatically communicated to other widgets. Alternatively, click Commit.
  4. Filter allows you to search for the data set. Below you see a list of GEO data sets with an ID number (link to the NCBI Data Set Browser), title, organism used in the experiment, number of samples, features, genes, subsets and a reference number for the PubMed journal (link to the article abstract).
  5. Short description of the experiment from which the data set is sourced.
  6. Select which Sample Annotations will be used in the output.

Example

GEO Data Sets is similar to the File widget. In the example below we selected Caffeine effect: time dose and response data set from the GEO data base and used Genes or spots as attributes. We inspected the data in Data Table. Then we selected 3 genes in the Select Columns widget for a detailed analysis in another data table.