A novel covariance function detecting timehifts between time series accounts for temporal mismatches between time series, (of replicates and samples) which share similar patterns, shifted in time. This allows for additional correction of confounding variation in time, as treatment might slow down reaction time of cell-cycle genes, leading to a bunch of falsely positive predicted non differential expressed genes downstream.
To enable timeshift detection add the flag -t to the run script. Timeshifts for all replicates will be reported in results.csv, where the order of replicates is the same order as in the input files FILE FILE (see Parameter options).